Can dish out a lot of burst damage while moving around quickly during team fights. This makes it very hard to catch him and kill him in a team fight.
Great objective control due to his Ultimate 
R. It can allow him to transition from a Dragon to Baron almost immediately. He can also pull backdoors off with this ability.
The CC on his 
W allows him to set plays for both himself and his team. This can be really effective if he manages to CC a high priority target, and get rid of them quickly.
Can’t really do much during the early game, especially if he is against something with hard CC or if he is getting camped.
Extremely item reliant and won’t dish out a lot of damage if he was set behind during the early and mid game.
His Ultimate R changes the positioning of him and anyone inside the circle. This can make Ryze outplay himself and get his entire team killed if proper vision is not set-up before the usage of the ability.
0 - 15 min
Focus on farming and getting as much gold and XP as possible. You need time and gold before you’re able to come online and deal damage.
Your champion is incredibly weak in the early game. Focus on farming and avoid fighting with the enemy until you’ve got an item behind you.
After your bot lane has moved to the mid lane, rotate to the bot side of the map or somewhere else on the map so you can continue to farm and gain XP. Do not fight anyone unless you have an advantage over them. Continue to get XP and gold.
15 - 25 min
At this stage of the game, you want to put yourself in a side lane and focus on farming so you have a stronger late game.
In the later parts of the mid-game and when the enemy starts to group, make sure you follow suit and start to group with your team.
Use your Ultimate R to get picks with your allies on enemies who are isolated or split up from their team. If you can catch someone out, try to take the Dragon or Baron afterwards.
25+ min
Stick with your team in the late game. Do not split up or walk away from them otherwise the enemy may try to pick you off or initiate a 4v5 fight when you’re away from your team.
Delay team fights while you dish out damage with your basic combos. Make sure you try to stay safe in team fights by watching your positioning and avoid overextending too much.
Ryze in the late game deals a lot of burst damage. Hide in high traffic areas if you’re ahead and look to blow someone up.
His 
E is pivotal to his success in the lane and the game. Combined with his 
Q, it can deal a lot of damage in a short time.
His W should help him make plays and catch enemies out. This will encourage his Jungler to gank him frequently.
Getting his Ultimate R will allow Ryze to be too mobile around the map. He can always be there for his team, especially when they are getting all-in'd.
Ryze will become more potent as he keeps getting his items. He should focus on farming during the early game for this.
His ability to teleport multiple people from one part of the map to another will help him rush neutral/enemy objectives present around the map.
His E Q combo and spread should dish out a lot of damage. Ryze's Passive will help him in the heat of the battle as Ryze will be able to kite easily.
Ryze is a monster during this phase of the game due to the short cooldowns of his ability, his burst damage, and his Passive.
His Ultimate R will have a massive range now. He should always look for objectives using this. He may even get a chance to backdoor the enemy.
His W will be a really potent pick tool during this phase of the game. The slow will help immensely if he manages to pick out a high priority target.
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