6 Cybernetic plays very similarly to set 3, except with the addition of Vayne, it will be much easier to powerspike before finding Ekko. Vayne is still a good carry, but with Infiltrator Spatula, Irelia will be a better carry than Vayne.
If you find early cybernetic units or find an early Irelia. Items are quite flexible, but lots of Sparring Gloves will help itemize Vayne to ensure a win streak.
Level up on 2 if you are strong and want to start a win streak. Level up to 5 after carousel on 4 if you want to continue your win streak.
If you are lose streaking up to round 7, you can level up to 5 if you don't think you can beat the creeps.
Level up to level 6 if you are on a win streak or level up to 5 if you haven't already. Win or lose, you should normally catch up to level 6 on Round 2. Roll if you're very weak or sitting on a lot of pairs.
If you're commiting to a fast 8 lose streaking or high rolling a win streak, you can level up to 7 early at Round 4 after the carousel. You should still have at least 40 gold after leveling and have a good unit to put in. Do not reroll until you hit level 8.
Before the fight at Round 1, level up to 7 if you haven't already and roll down to find at least Vayne 2 and 6 Cybernetic if you can.
After 7 raptors, level to 8 if you haven't already and roll down to complete your team.
If you're playing a Fast 8: you can level up to 8 at Round 3 to look for 5 cost units before other players. Alternatively, if you can level to 8 at Round 1 and have 40+ gold left over, you can level up earlier than most other players who fast 8. You should also level up to 8 if you fall below ~30 health, assuming you were lose streaking to this point.
The key is distributing your items well between your Cybernetics. Items like Cloaks and Tears can go on Leona and Fiora as they don't build into your carry items.
If you don't have all 6 Cybernetics, try to fit in Sniper or Blademaster depending on whether you found Irelia or Vayne. Use this to stay strong to eventually hit 6 Cybernetics.
Cybernetic units do great with only one item, so try to use items like Belt, Tear, or Cloak early on your units like Leona or Fiora. These can build into items like Redemption or Ionic Spark.
Lucian can do well in the midgame with only 1 item like Red Buff to allow you to win streak before you find Irelia or Vayne.
Now that we have Vayne, we can reach 6 Cybernetics at level 6/7 easily so you do not have to rush level 8 and pray for an Ekko. Stabilize with Vayne as your carry in the midgame, using units like Irelia and Ekko as your secondary carries.
Always try to place Snipers furthest away from enemies to make use of their trait.
Only use Thresh over Caitlyn if he's two star and have a good unit to pull in, or if you don't have a 3 item Vayne carry.