Last updated 2 days ago for 10.16 Patch
6 Cybernetic plays very similarly to set 3, except with the addition of Vayne, it will be much easier to powerspike before finding Ekko. Vayne and Irelia are both solid carries for the team, adding more flexibility to the comp.
If you find early cybernetic units or find an early Irelia. Items are quite flexible but especially if you start with lots of Sparring Gloves for Irelia you can look to streak to 8 quickly.
The key is distributing your items well between your Cybernetics. Items like Cloaks and Tears can go on Leona and Fiora as they don't build into your carry items.
If you don't have all 6 Cybernetics, try to fit in Sniper or Blademaster depending on whether you found Irelia or Vayne. Use this to stay strong to eventually hit 6 Cybernetics.