Always watch your positioning during the laning phase. Try and stay at max distance so it’s harder for her to root you with her E. This will also make it harder for her to get a good Ultimate R off as she has to close the gap in order to stun you.
Stand outside of the minion wave at all times if possible. This will make it harder for Neeko to push and poke you at the same time with her Q.
Once Neeko has her Ultimate R, her kill pressure will increase. Make sure you back when low whenever she has her Ultimate R up.
Disengage is your best friend when dealing with Neeko and her Ultimate R in team fights. Disengage as soon as Neeko walks forward and tries to engage to minimize the usefulness of her Ultimate R.
Ward your flanks and nearby bushes when sieging objectives as Neeko may use her Passive and W to get a good engage off with her Ultimate R.
Splitting up and not standing too close together will help reduce how many people Neeko and stun with her Ultimate R. Group when team fighting, but don’t stand too close together.
Once Neeko hits level 6, her kill pressure intensifies. When fighting her, keep in mind that she can cast her Ultimate R and deal damage and CC you.
When Neeko has completed her first item, she will have tons of wave clear and will be able to push the wave very fast. You’ll need to make sure you can push the wave back so you don’t lose your Tower early.
Neeko is good in team fights thanks to her Ultimate R. Disengage as soon as you see her channel her Ultimate R.