
Karthus·Runes for Mid
Power Spike





Tier | D- |
Win rate | 50.3% |
Pick rate | 0.4% |
Ban rate | 4.2% |
Matches | 551- |

Karthus Runes

Domination / Precision
Win Rate 50.0% and PickRate 42.1% based on 232 matches
Keystone options
In patch 13.11, Dark Harvest Karthus has 50.0% winrate in Mid. Within primary rune tree, the best runes would be Taste of Blood, Eyeball Collection and Ultimate Hunter. In the secondary tree the most popular runes are Presence of Mind and Last Stand.
Domination










Precision









Karthus Matchups Overview
Karthus General information
Karthus tips and tricks
Farm with Q in the early game to make it easier for your to pick up CS.
Deactivate your Defile E once the skirmish has finished as it will eat through your mana bar.
Keep an eye on the minimap at all times and use your R to pick up kills on low health
Karthus combos
Every combo you need to master the champion!

Probuilds
Check out the latest and best Karthus Probuilds used by pros from around the world, featured by lolvvv.

Champion Leaderboards
Discover the top Karthus mains and one-tricks from different regions on the player leaderboard at OPGG.

In-depth Build Stats
Dive into even more Karthus builds stats with additional analysis from our friends at LoLalytics.