Karthus · Combos

To engage Q W E as fast as you can and instantly Flash forward, followed by hitting Q as many times as you can.

When at mid range Q W instantly followed by using E on your target. AA and right after use two Q's for every AA.

If you're looking to deal damage as you retreat Q W instantly then R and F near the beginning of the cast animation.

If you happen to die Q W instantly followed by two Q's. Use R quickly then one last Q as soon as the R channel finishes.

When at close range E AA instantly followed by Q and using AA's in between every Q cast.

When at long range W Q your target instantly then walk forward and E right before you are in range, then continue to use Q.